Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.52 |
| ▸ | PDE4A | P27815 | 15/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325303 | 0.89 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL8319816 | 0.88 | PDE4D (0.63) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL8324241 | 0.84 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL8320435 | 0.82 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5022775 | 0.80 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL8323847 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL8264976 | 0.77 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL8326127 | 0.77 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL8319231 | 0.77 | PDE4D (0.58) | PDE4DPDE4BPDE4APDE4CGFER | |
| Hydrochloric Acid SCHEMBL74596 | 0.77 | PDE4D (0.58) | PDE4DPDE4BPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |