Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 14/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 11/20 | 0.48 |
| ▸ | PGR | P06401 | 9/20 | 0.48 |
| ▸ | AR | P10275 | 9/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091161 | 0.85 | NR3C2 (0.47) | NR3C2NR3C1PGRAR | |
| SCHEMBL6091813 | 0.82 | NR3C2 (0.48) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6091874 | 0.81 | NR3C2 (0.46) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6090744 | 0.81 | NR3C2 (0.46) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6091165 | 0.80 | NR3C1 (0.53) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6091273 | 0.79 | NR3C2 (0.54) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6088923 | 0.79 | NR3C2 (0.53) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6090592 | 0.79 | NR3C2 (0.46) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6091761 | 0.79 | NR3C2 (0.46) | NR3C2NR3C1PGRARPLA2G7 | |
| SCHEMBL6090543 | 0.79 | NR3C1 (0.57) | NR3C2NR3C1PGRARPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |