Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187258 | 0.82 | MEN1 (0.49) | SMN1; SMN2KDM4EALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5027835 | 0.82 | LMNA (0.43) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2033890 | 0.80 | LMNA (0.42) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18135259 | 0.80 | LMNA (0.42) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1453001 | 0.79 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6828423 | 0.79 | LMNA (0.41) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1931354 | 0.78 | KDM4E (0.51) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13708391 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL15912538 | 0.76 | KDM4E (0.41) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL21253055 | 0.75 | LMNA (0.44) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |