Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711664 | 0.78 | NR1H4 (0.74) | MAPTPOLBNR1H4KMT2AGAA | |
| SCHEMBL10428429 | 0.77 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 (0.53) | MAPTPOLB | |
| SCHEMBL28813458 | 0.75 | CACNA1B (0.59) | MAPTPOLBKMT2AGAAALDH1A1 | |
| SCHEMBL9196928 | 0.74 | HPGD (0.57) | MAPTPOLBKMT2AGAAALDH1A1 | |
| SCHEMBL2462911 | 0.74 | KDM4E (0.71) | MAPTPOLBKMT2AGAAATM | |
| SCHEMBL11321541 | 0.73 | MAPT (0.56) | MAPTPOLBNR1H4KMT2AGAA | |
| SCHEMBL24212418 | 0.73 | NR1H4 (1.00) | MAPTPOLBNR1H4KMT2AGAA | |
| SCHEMBL12323555 | 0.73 | NR1H4 (0.74) | MAPTPOLBNR1H4KMT2AGAA | |
| SCHEMBL11143326 | 0.73 | ESRRA (0.62) | MAPTPOLBNR1H4GAAATM | |
| SCHEMBL27372539 | 0.73 | KDM4E (0.69) | MAPTPOLBKMT2AGAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | claimed |
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | disclosed |