Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESRRA | P11474 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288143 | 0.88 | NR1H4 (0.79) | NR1H4MAPTPOLBL3MBTL1ESRRA | |
| SCHEMBL9453262 | 0.85 | NR1H4 (0.75) | NR1H4MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL12323555 | 0.85 | NR1H4 (0.74) | NR1H4MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL27974311 | 0.84 | TDP1 (0.59) | NR1H4MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL38654691 | 0.83 | MAPT (0.58) | NR1H4MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL7711402 | 0.83 | KMT2A (0.60) | NR1H4MAPTPOLBTDP1L3MBTL1 | |
| Benzoic Acid SCHEMBL20548505 | 0.81 | ALDH1A1 (0.56) | NR1H4MAPTPOLBKMT2AMEN1 | |
| SCHEMBL9743282 | 0.80 | KMT2A (0.66) | MAPTPOLBTDP1L3MBTL1KMT2A | |
| SCHEMBL11143326 | 0.79 | ESRRA (0.62) | NR1H4MAPTPOLBL3MBTL1ESRRA | |
| SCHEMBL8324420 | 0.78 | MAPT (0.69) | NR1H4MAPTPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358515-B2 | ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| US-20010008893-A1 | HYDROQUINONE DERIVATIVES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-19 | — | — | US | disclosed |
| EP-0972766-A1 | HYDROQUINONE DERIVATIVES | Senju Pharmaceutical Co., Ltd. (JP) | 2000-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008893-A1 | HYDROQUINONE DERIVATIVES | REN, AGTR1, AGTR2 | NR1H4 2599/4885MAPT 4729/4885POLB 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.