Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94886 | 0.96 | TDP1 (0.75) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL95198 | 0.89 | TDP1 (0.79) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL98294 | 0.88 | TDP1 (0.83) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL8214391 | 0.88 | TDP1 (0.83) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL96371 | 0.88 | TDP1 (0.83) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL1052631 | 0.84 | TDP1 (0.86) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL7068671 | 0.84 | TDP1 (0.95) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL4559590 | 0.84 | SMN1; SMN2 (0.67) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL8519287 | 0.82 | TDP1 (1.00) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL27516050 | 0.82 | TDP1 (1.00) | TDP1MAPTL3MBTL1LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977170-A | HIGH DENISTY LIPOPROTEINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1998057927-A1 | ELEVATION OF HDL CHOLESTEROL BY 4-[(AMINOTHIOXOMETHYL)HYDRAZONO]-4-ARYLBUTYL CARBAMATES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |