Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.70 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.70 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96371 | 0.98 | TDP1 (0.83) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL98294 | 0.98 | TDP1 (0.83) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL8214391 | 0.98 | TDP1 (0.83) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL94886 | 0.93 | TDP1 (0.75) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7068671 | 0.91 | TDP1 (0.95) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| Ethylene SCHEMBL8324469 | 0.89 | TDP1 (0.69) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| Acetaldehyde SCHEMBL27387803 | 0.89 | L3MBTL1 (0.69) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL8519287 | 0.89 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL27516050 | 0.89 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL9057671 | 0.89 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114099794-A | Bioabsorbable orthopedic implant material and preparation method thereof | 北京航空航天大学 | 2022-03-01 | — | — | CN | claimed |
| US-9999218-B2 | Pest control formulations and methods of making and using same | 0903608 B.C. LTD. (US) | 2018-06-19 | — | — | US | claimed |
| EP-0757771-A1 | PROCESS AND DEVICE FOR RENEWING OR REPAIRING PIPELINES | INC BAUCHEMIE AG (CH) | 1997-02-12 | — | — | EP | claimed |
| WO-1995029361-A1 | PROCESS AND DEVICE FOR RENEWING OR REPAIRING PIPELINES | INC BAUCHEMIE AG (CH) | 1995-11-02 | — | — | WO | claimed |
| EP-0369398-A2 | Polyphosphazene derivatives containing carbonyl groups suitable for photoreticulation processes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-05-23 | — | — | EP | claimed |
| US-11918658-B2 | Hydrogels and related compositions and methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-03-05 | — | — | US | disclosed |
| US-11912705-B2 | Cathinone derivatives, pharmaceutical formulations, and methods | THE CORPORATION OF MERCER UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20220331444-A1 | HYDROGELS AND RELATED COMPOSITIONS AND METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-10-20 | — | — | US | disclosed |
| US-10603313-B2 | Allosteric modulators of the mu opioid receptor | Chiromics, LLC (US) | 2020-03-31 | — | — | US | disclosed |
| CN-110404062-A | Immunomodulator and application thereof | UNIV QUEENSLAND | 2019-11-05 | — | — | CN | disclosed |
| US-20190030020-A1 | Allosteric Modulators of the Mu Opioid Receptor | Chiromics, LLC (US) | 2019-01-31 | — | — | US | disclosed |
| CN-107753499-A | For treating the Compounds and methods for of virus infection | 春堤制药公司 | 2018-03-06 | — | — | CN | disclosed |
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4920221-A | CENTRAL NERVOUS SYSTEM ACTIVE AGENTS | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4642373-A | Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents | PFIZER INC. (US) | 1987-02-10 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |
| US-4576964-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1986-03-18 | — | — | US | disclosed |
| US-4476131-A | ANTIEMETICS, ANALGESICS | PFIZER INC. (US) | 1984-10-09 | — | — | US | disclosed |
| US-4473704-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10603313-B2 | Allosteric modulators of the mu opioid receptor | OPRM1, OPRK1, OPRD1 | TDP1 3598/4885L3MBTL1 761/4885MAPT 1331/4885 |
| US-20190030020-A1 | Allosteric Modulators of the Mu Opioid Receptor | OPRM1, OPRK1, OPRD1 | TDP1 4457/4885L3MBTL1 2224/4885MAPT 2178/4885 |
| US-11912705-B2 | Cathinone derivatives, pharmaceutical formulations, and methods | TACR2, TACR1, ADRA2C | TDP1 2704/4885L3MBTL1 4883/4885MAPT 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.