Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887767 | 0.85 | KMT2A (0.68) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL5343785 | 0.83 | ALDH1A1 (0.66) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL1874186 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL12793685 | 0.82 | ALDH1A1 (0.72) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL28003774 | 0.82 | ALDH1A1 (0.72) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL28113726 | 0.82 | ALDH1A1 (0.68) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL14484120 | 0.81 | ALDH1A1 (0.66) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL3562140 | 0.79 | ALDH1A1 (0.64) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL13712056 | 0.79 | ALDH1A1 (0.64) | ALDH1A1POLBTDP1LMNAMEN1 | |
| SCHEMBL10288218 | 0.78 | POLB (0.63) | ALDH1A1POLBTDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635018-B1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO TECHNOLOGY (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5516783-A | PLATELET ACTIVATING FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0635018-A1 | 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993016075-A1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |