Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452483 | 0.88 | TDP1 (0.52) | ALDH1A1TDP1MAPTL3MBTL1TSHR | |
| SCHEMBL6556643 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30559692 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11206055 | 0.81 | APEX1 (0.48) | ALDH1A1LMNACYP1A2CYP2C19KDM4E | |
| SCHEMBL30111052 | 0.80 | MEN1 (0.54) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4770160 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8462873 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8327255 | 0.80 | MEN1 (0.54) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6556671 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11264770 | 0.76 | APEX1 (0.44) | ALDH1A1LMNACYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| EP-0775693-A1 | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfides and 2-amino-6-chlorophenyl-isopropylsulfide | BAYER AG (DE) | 1997-05-28 | — | — | EP | claimed |
| EP-0711754-B1 | Process for preparing 2-chloro-6-nitrophenylalkylsulfides as well as novel 2-chloro-6-nitrophenyl alkylsulfides | BAYER AG (DE) | 1999-03-10 | — | — | EP | disclosed |
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| US-5650542-A | Process for the preparation of 2-chloro-6-nitrophenyl alkyl sulphides and novel 2-chloro-6-nitrophenyl alkyl sulphides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0775693-A1 | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfides and 2-amino-6-chlorophenyl-isopropylsulfide | BAYER AG (DE) | 1997-05-28 | — | — | EP | disclosed |
| EP-0711754-A1 | Process for preparing 2-chloro-6-nitrophenylalkylsulfides as well as novel 2-chloro-6-nitrophenyl alkylsulfides | BAYER AG (DE) | 1996-05-15 | — | — | EP | disclosed |