Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.49 |
| ▸ | PGR | P06401 | 10/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.49 |
| ▸ | AR | P10275 | 10/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 7/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322122 | 0.88 | NR3C1 (0.51) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6089111 | 0.88 | NR3C1 (0.46) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6090475 | 0.86 | NR3C1 (0.54) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6089494 | 0.84 | NR3C1 (0.67) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6090802 | 0.83 | NR3C1 (0.48) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6091256 | 0.82 | NR3C1 (0.47) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6091219 | 0.82 | NR3C1 (0.47) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6092179 | 0.81 | NR3C2 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL6091677 | 0.81 | NR3C1 (0.53) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL8324764 | 0.80 | NR3C1 (0.45) | NR3C1PGRNR3C2ARPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |