Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.69 |
| ▸ | MAPT | P10636 | 11/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824515 | 0.86 | MAPT (0.64) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL30953903 | 0.86 | MAPT (0.64) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL14784645 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL20598544 | 0.85 | GAA (0.69) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL30501419 | 0.85 | GAA (0.69) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL18347278 | 0.84 | MAPT (0.54) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL22954566 | 0.84 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL22094933 | 0.80 | MAPT (0.97) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL12684759 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL3536564 | 0.80 | MAPT (0.97) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |