SCHEMBL8324967

SCHEMBL8324967

CCCC(=O)[C@H](Cc1nc(C)c(-c2ccccc2)o1)NC(=O)C1(C[C@@H](CCOC)C(=O)O)CCCC1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MME P08473 17/20 0.63
NPPA P01160 5/20 0.63
MMP1 P03956 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331455 0.92 MME (0.73) MMENPPAMMP1
SCHEMBL6806869 0.91 MME (0.64) MMENPPAMMP1
SCHEMBL6806867 0.91 MME (0.64) MMENPPAMMP1
SCHEMBL6259877 0.83 MME (0.59) MMENPPAMMP1
SCHEMBL8334926 0.83 MME (0.58) MMENPPAMMP1
SCHEMBL6807616 0.77 MME (0.72) MMENPPAMMP1
SCHEMBL6807360 0.77 MME (0.73) MMENPPAMMP1
SCHEMBL6255996 0.77 MME (0.73) MMENPPAMMP1
SCHEMBL6812175 0.77 MME (0.73) MMENPPAMMP1
SCHEMBL6808018 0.73 MME (0.68) MMENPPA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004056787-A1 CYCLOPENTYL GLUTARAMIDES AND THEIR USE AS NEUTRAL ENDOPEPTIDASE INHIBITORS PFIZER LIMITED (GB) 2004-07-08 WO disclosed