Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 16/20 | 0.58 |
| ▸ | NPPA | P01160 | 7/20 | 0.58 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806867 | 0.92 | MME (0.64) | MMENPPAMMP1ITGB1ITGA4 | |
| SCHEMBL6806869 | 0.92 | MME (0.64) | MMENPPAMMP1ITGB1ITGA4 | |
| SCHEMBL8331455 | 0.85 | MME (0.73) | MMENPPAMMP1ITGB1ITGA4 | |
| SCHEMBL8324967 | 0.83 | MME (0.63) | MMENPPAMMP1 | |
| SCHEMBL6807892 | 0.80 | MME (0.55) | MMENPPA | |
| SCHEMBL6807888 | 0.80 | MME (0.55) | MMENPPA | |
| SCHEMBL8275076 | 0.80 | MME (0.56) | MMENPPAMMP1 | |
| SCHEMBL8337080 | 0.78 | MME (0.39) | MMENPPAMMP1ITGB1ITGA4 | |
| SCHEMBL6259877 | 0.77 | MME (0.59) | MMENPPAMMP1 | |
| SCHEMBL6807209 | 0.77 | MME (0.57) | MMENPPAMMP1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056787-A1 | CYCLOPENTYL GLUTARAMIDES AND THEIR USE AS NEUTRAL ENDOPEPTIDASE INHIBITORS | PFIZER LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |