Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.76 |
| ▸ | ITGAV | P06756 | 20/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.76 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.71 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2836388 | 0.96 | ITGB3 (0.70) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL8336940 | 0.93 | ITGB3 (0.78) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL8335645 | 0.91 | ITGB3 (0.78) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL2842108 | 0.91 | ITGB3 (0.73) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL8336984 | 0.90 | ITGB3 (0.76) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Hydrochloric Acid SCHEMBL2843122 | 0.89 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL8337583 | 0.89 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL8332826 | 0.89 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL2836389 | 0.89 | ITGB3 (0.61) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL2839348 | 0.89 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |