Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321345 | 1.00 | PTGER4 (0.55) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8321350 | 1.00 | PTGER4 (0.55) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8322642 | 0.91 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8322645 | 0.91 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8327004 | 0.91 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8323838 | 0.86 | PTGER1 (0.57) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8323833 | 0.86 | PTGER1 (0.57) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8322341 | 0.82 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8319700 | 0.82 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1APP | |
| SCHEMBL8319694 | 0.82 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |