Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303645 | 0.90 | CYP1B1 (0.57) | XDHNPSR1LMNAMAPTCYP1B1 | |
| SCHEMBL7308871 | 0.83 | CYP1B1 (0.56) | XDHLMNAMAPTCYP1B1 | |
| SCHEMBL7316873 | 0.82 | CYP1B1 (0.57) | XDHEGFRRETKDRNPSR1 | |
| SCHEMBL7311118 | 0.82 | CYP1B1 (0.57) | XDHNPSR1LMNAMAPTCYP1B1 | |
| SCHEMBL7306885 | 0.81 | CYP1B1 (0.54) | XDHEGFRKDM5ACYP1B1 | |
| SCHEMBL7307391 | 0.81 | CYP1B1 (0.53) | XDHEGFRRETKDRQPCT | |
| SCHEMBL7316709 | 0.81 | CYP1B1 (0.53) | XDHEGFRRETKDRMAPT | |
| SCHEMBL7313359 | 0.80 | CYP1B1 (0.55) | XDHMAPTCYP1B1 | |
| SCHEMBL7306588 | 0.80 | PPARG (0.57) | XDHEGFRMAPTCYP1B1 | |
| SCHEMBL7310036 | 0.80 | CYP1B1 (0.55) | XDHEGFRRETKDRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047817-A1 | PDE4 AND PDE3/4 INHIBITORS FOR USE IN THE TREATMENT OF CACHEXIA | ALTANA PHARMA AG (DE) | 2004-06-10 | — | — | WO | disclosed |