Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324795 | 0.84 | MIF (0.38) | LMNAITGB3ITGAVITGB6KDM4E | |
| SCHEMBL6263545 | 0.84 | FFAR1 (0.51) | FFAR1KDM1ALMNAMAOANNMT | |
| SCHEMBL2437089 | 0.81 | HTR2C (0.54) | FFAR1KDM1ALMNAMAOAMEN1 | |
| SCHEMBL15797925 | 0.81 | HTR2C (0.54) | FFAR1KDM1ALMNAMAOAMEN1 | |
| SCHEMBL6267026 | 0.79 | FFAR1 (0.46) | FFAR1KDM1ALMNAMAOANNMT | |
| SCHEMBL8335519 | 0.79 | FFAR1 (0.44) | FFAR1KDM1ALMNATRPM5MAOA | |
| SCHEMBL2428840 | 0.78 | MIF (0.47) | KDM1ALMNAKMT2AKDM4EMAPT | |
| SCHEMBL15798206 | 0.77 | HTR2A (0.47) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL17259159 | 0.77 | HTR2A (0.47) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7885591 | 0.76 | KDM1A (0.43) | FFAR1KDM1ALMNAMAOANNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |