Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGAV | P06756 | 5/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886127 | 0.87 | KDM1A (0.46) | FFAR1ITGB3ITGAVITGB6KDM1A | |
| SCHEMBL8325401 | 0.84 | FFAR1 (0.46) | FFAR1ITGB3ITGAVITGB6KDM1A | |
| SCHEMBL6267026 | 0.84 | FFAR1 (0.46) | FFAR1ITGB3ITGAVITGB6KDM1A | |
| SCHEMBL8335519 | 0.83 | FFAR1 (0.44) | FFAR1ITGB3ITGAVITGB6KDM1A | |
| SCHEMBL22169320 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVITGB6ITGB1ITGB5 | |
| SCHEMBL21847837 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVITGB6ITGB1ITGB5 | |
| SCHEMBL18983876 | 0.79 | CHRNA7 (0.53) | FFAR1KDM1ALMNACHRNA7MAOA | |
| SCHEMBL2435013 | 0.79 | HTR2C (0.59) | FFAR1ITGB3ITGAVITGB6KDM1A | |
| SCHEMBL6264316 | 0.79 | ITGB3 (0.44) | FFAR1ITGB3ITGAVITGB6KDM1A | |
| SCHEMBL20595049 | 0.78 | KDM1A (0.45) | ITGB3ITGAVITGB6KDM1AITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592421-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Corporation (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050043344-A1 | Heteroarylalkanoic acids as integrin receptor antagonists derivatives | PHARMACIA CORPORATION | 2005-02-24 | — | — | US | disclosed |
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043344-A1 | Heteroarylalkanoic acids as integrin receptor antagonists derivatives | ITGA5, ITGAV, ITGA6 | FFAR1 100/4885ITGB3 6/4885ITGAV 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.