Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327437 | 0.91 | ACAT1 (0.68) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL8325381 | 0.91 | ACAT1 (0.62) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL6636791 | 0.90 | ACAT1 (0.60) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL8331189 | 0.90 | ACAT1 (0.65) | ACAT1SOAT1 | |
| SCHEMBL6636574 | 0.90 | ACAT1 (0.75) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL8325491 | 0.90 | ACAT1 (0.64) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL6634606 | 0.89 | ACAT1 (0.60) | ACAT1SOAT1 | |
| SCHEMBL8326341 | 0.89 | ACAT1 (0.74) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL6634432 | 0.89 | ACAT1 (0.61) | ACAT1SOAT1ADORA2AADORA1PDE4A | |
| SCHEMBL6636746 | 0.89 | ACAT1 (0.60) | ACAT1SOAT1ADORA2AADORA1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |