Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328218 | 1.00 | OXTR (0.40) | OXTRAVPR1AMAPTPKMYAP1 | |
| SCHEMBL8325802 | 1.00 | OXTR (0.40) | OXTRAVPR1AMAPTPKMYAP1 | |
| SCHEMBL8327746 | 0.90 | OXTR (0.39) | OXTRAVPR1AMAPTPKMYAP1 | |
| SCHEMBL8331110 | 0.90 | OXTR (0.39) | OXTRAVPR1AMAPTPKMYAP1 | |
| SCHEMBL8327750 | 0.90 | OXTR (0.39) | OXTRAVPR1AMAPTPKMYAP1 | |
| SCHEMBL8328914 | 0.85 | SLC6A2 (0.40) | OXTRAVPR1AYAP1TEAD4TEAD2 | |
| SCHEMBL8326122 | 0.84 | HTR2A (0.38) | OXTRAVPR1APKMYAP1TEAD4 | |
| SCHEMBL8331211 | 0.84 | HTR2A (0.38) | OXTRAVPR1APKMYAP1TEAD4 | |
| SCHEMBL8326125 | 0.84 | HTR2A (0.38) | OXTRAVPR1APKMYAP1TEAD4 | |
| SCHEMBL8326129 | 0.84 | HTR2A (0.38) | OXTRAVPR1APKMYAP1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |