Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.69 |
| ▸ | PGR | P06401 | 9/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.69 |
| ▸ | AR | P10275 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090405 | 1.00 | NR3C1 (0.69) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL6090257 | 0.96 | NR3C1 (0.67) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL6089796 | 0.94 | NR3C1 (0.69) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL6091030 | 0.85 | NR3C1 (0.51) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL1349350 | 0.84 | NR3C1 (0.48) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL8321218 | 0.83 | NR3C1 (0.82) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL8325656 | 0.82 | NR3C2 (0.81) | NR3C1PGRNR3C2AR | |
| SCHEMBL6089733 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL8320352 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6090200 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2ARPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |