Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370883 | 0.87 | LMNA (0.58) | DRD4CCR3KCNH2MEN1LMNA | |
| SCHEMBL1502120 | 0.85 | DRD4 (0.59) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30211803 | 0.83 | CCR3 (0.67) | DRD4CCR3KCNH2MEN1LMNA | |
| SCHEMBL1810572 | 0.83 | CCR3 (0.67) | DRD4CCR3KCNH2MEN1LMNA | |
| SCHEMBL8327676 | 0.83 | DRD4 (0.64) | DRD4CCR3HIF1AEPAS1KCNH2 | |
| SCHEMBL1810573 | 0.83 | CCR3 (0.67) | DRD4CCR3KCNH2MEN1LMNA | |
| SCHEMBL30211808 | 0.82 | DRD4 (0.56) | DRD4MCHR1CCR3KCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL30211801 | 0.82 | CCR3 (0.66) | DRD4CCR3KCNH2MEN1LMNA | |
| SCHEMBL4021903 | 0.82 | CCR3 (0.58) | DRD4MCHR1CCR3KCNH2MEN1 | |
| SCHEMBL5777552 | 0.81 | CCR3 (0.75) | DRD4MCHR1CCR3HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |