Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 3/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325000 | 0.96 | ELANE (0.40) | ELANECA2HSD11B1CYP3A4ABCC9 | |
| SCHEMBL8325533 | 0.90 | ELANE (0.36) | ELANECA2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8321680 | 0.90 | ELANE (0.36) | ELANECA2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8323469 | 0.84 | ELANE (0.50) | ELANECA2HSD11B1KDM1A | |
| SCHEMBL8319678 | 0.83 | ELANE (0.55) | ELANECA2GPR119KDM1ASTS | |
| SCHEMBL8648957 | 0.83 | ELANE (0.38) | ELANECA2HSD11B1CYP3A4ABCC9 | |
| SCHEMBL8648000 | 0.83 | ELANE (0.38) | ELANECA2HSD11B1CYP3A4ABCC9 | |
| SCHEMBL8323039 | 0.81 | PSEN1 (0.44) | KAT6A | |
| SCHEMBL8648382 | 0.80 | CYP3A4 (0.39) | ELANECA2HSD11B1CYP3A4ABCC9 | |
| SCHEMBL8646164 | 0.80 | CYP3A4 (0.39) | ELANECA2HSD11B1CYP3A4ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |