SCHEMBL8323469

SCHEMBL8323469

CC(C)(C)OC(=O)Oc1ccc(S(OS(C)(=O)=O)(c2ccccc2)c2ccc(OC(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.50
HSD11B1 P28845 1/20 0.40
KDM1A O60341 1/20 0.39
CA2 P00918 1/20 0.39
MMP13 P45452 5/20 0.38
NPY2R P49146 2/20 0.37
MMP2 P08253 3/20 0.37
MAPT P10636 3/20 0.36
MMP1 P03956 2/20 0.36
POLB P06746 1/20 0.36
PKM P14618 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319678 0.94 ELANE (0.55) ELANEKDM1ACA2MAPTPOLB
SCHEMBL8325000 0.88 ELANE (0.40) ELANEHSD11B1CA2MMP13
SCHEMBL8319947 0.86 ELANE (0.47) ELANEKDM1ACA2MMP13MAPT
SCHEMBL8323482 0.86 ELANE (0.47) ELANEKDM1ACA2MMP13MAPT
SCHEMBL8325780 0.84 ELANE (0.43) ELANEHSD11B1KDM1ACA2
SCHEMBL8647646 0.83 ELANE (0.44) ELANEHSD11B1KDM1ACA2MMP13
SCHEMBL8643863 0.83 ELANE (0.44) ELANEHSD11B1KDM1ACA2MMP13
SCHEMBL8649154 0.83 ELANE (0.44) ELANEHSD11B1KDM1ACA2MMP13
SCHEMBL8969045 0.82 ELANE (0.51) ELANEHSD11B1KDM1ACA2MMP13
SCHEMBL8319093 0.81 PTPN1 (0.48) CA2MAPTPOLBPKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880169-A HAVING HIGH RESOLUTION FOR FINE PATTERNING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-09 US disclosed