Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265815 | 0.94 | KEAP1 (0.34) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL4207156 | 0.90 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL853328 | 0.88 | CSNK2A1 (0.36) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL23530252 | 0.87 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL30918942 | 0.86 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL6322357 | 0.85 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL4253521 | 0.83 | EGFR (0.40) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL6266493 | 0.83 | CSNK2A1 (0.35) | CSNK2A1CSNK2A2EGFRBTKUSP30 | |
| SCHEMBL8334943 | 0.83 | USP2 (0.36) | CSNK2A1CSNK2A2USP2SMN1; SMN2 | |
| SCHEMBL8326067 | 0.82 | MAPT (0.42) | CSNK2A1CSNK2A2EGFRBTKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |