Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638307 | 0.88 | KDM4E (0.41) | NAMPTKDM4EPKMDRD2KMT2A | |
| SCHEMBL14493183 | 0.88 | NAMPT (0.41) | NAMPTKDM4EPKMDRD2KMT2A | |
| SCHEMBL8319012 | 0.88 | NAMPT (0.41) | NAMPTKDM4EPKMDRD2KMT2A | |
| SCHEMBL5343772 | 0.88 | NAMPT (0.41) | NAMPTKDM4EPKMDRD2KMT2A | |
| SCHEMBL3272782 | 0.84 | KDM4E (0.46) | NAMPTKDM4EPKMKMT2AMEN1 | |
| SCHEMBL13382577 | 0.84 | KDM4E (0.46) | NAMPTKDM4EPKMKMT2AMEN1 | |
| SCHEMBL13382306 | 0.84 | KDM4E (0.46) | NAMPTKDM4EPKMKMT2AMEN1 | |
| SCHEMBL5341676 | 0.83 | NAMPT (0.44) | NAMPTKDM4EPKMDRD2KMT2A | |
| SCHEMBL8327697 | 0.82 | NAMPT (0.39) | NAMPTKDM4EPKMDRD2KMT2A | |
| SCHEMBL8322581 | 0.81 | CHRM2 (0.40) | NAMPTKDM4EPKMDRD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962468-A | ANTIBACTERIAL ACTIVITY | LG CHEMICAL LTD. (KR) | 1999-10-05 | — | — | US | disclosed |
| EP-0688772-B1 | Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG CHEMICAL LTD (KR) | 1999-05-06 | — | — | EP | disclosed |
| US-5869670-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1999-02-09 | — | — | US | disclosed |
| US-5840916-A | INTERMEDIATE FOR QUINOLONE ANTIBIOTICS; 4-AMINOMETHYL-3-METHOXYIMINOPYRROLIDINE | LG CHEMICAL LTD. (KR) | 1998-11-24 | — | — | US | disclosed |
| US-5698570-A | QUINOLONE ANTIBIOTIC; BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-12-16 | — | — | US | disclosed |
| US-5633262-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-05-27 | — | — | US | disclosed |
| EP-0688772-A1 | Novel quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG Chemical Limited (KR) | 1995-12-27 | — | — | EP | disclosed |