Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322581 | 0.90 | CHRM2 (0.40) | NAMPTCHRM2CHRM1KDM4EPKM | |
| SCHEMBL5343772 | 0.85 | NAMPT (0.41) | NAMPTKDM4EPKMMEN1KMT2A | |
| SCHEMBL8319012 | 0.85 | NAMPT (0.41) | NAMPTCHRM2CHRM1KDM4EPKM | |
| SCHEMBL14493183 | 0.85 | NAMPT (0.41) | NAMPTKDM4EPKMMEN1KMT2A | |
| SCHEMBL8325977 | 0.82 | NAMPT (0.42) | NAMPTKDM4EPKMMEN1KMT2A | |
| SCHEMBL8466304 | 0.81 | NAMPT (0.44) | NAMPTKDM4EPKMKMT2ADRD2 | |
| SCHEMBL5341676 | 0.76 | NAMPT (0.44) | NAMPTKDM4EPKMMEN1KMT2A | |
| SCHEMBL27638307 | 0.73 | KDM4E (0.41) | NAMPTKDM4EPKMMEN1KMT2A | |
| SCHEMBL13646937 | 0.71 | HTT (0.46) | NAMPTKDM4EPKMMAPTDRD2 | |
| SCHEMBL3836086 | 0.71 | HTT (0.46) | NAMPTKDM4EPKMMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962468-A | ANTIBACTERIAL ACTIVITY | LG CHEMICAL LTD. (KR) | 1999-10-05 | — | — | US | disclosed |
| EP-0688772-B1 | Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG CHEMICAL LTD (KR) | 1999-05-06 | — | — | EP | disclosed |
| US-5698570-A | QUINOLONE ANTIBIOTIC; BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-12-16 | — | — | US | disclosed |
| US-5633262-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-05-27 | — | — | US | disclosed |
| EP-0688772-A1 | Novel quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG Chemical Limited (KR) | 1995-12-27 | — | — | EP | disclosed |