Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325990 | 0.92 | ADORA3 (0.44) | ADORA3TRPV1SIRT2SIRT1MEN1 | |
| SCHEMBL8325678 | 0.88 | ADORA3 (0.42) | ADORA3TRPV1 | |
| SCHEMBL8323291 | 0.88 | ADORA3 (0.43) | ADORA3TRPV1 | |
| SCHEMBL8523663 | 0.88 | ADORA3 (0.42) | ADORA3TRPV1 | |
| SCHEMBL8330375 | 0.87 | ADORA3 (0.42) | ADORA3TRPV1 | |
| SCHEMBL7864225 | 0.87 | ADORA3 (0.41) | ADORA3 | |
| SCHEMBL8328477 | 0.85 | ADORA3 (0.39) | ADORA3TRPV1 | |
| SCHEMBL8523478 | 0.85 | ADORA3 (0.43) | ADORA3 | |
| SCHEMBL8328175 | 0.84 | ADORA3 (0.38) | ADORA3TRPV1 | |
| SCHEMBL9727055 | 0.84 | PTAFR (0.42) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |