Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675514 | 0.90 | KMT2A (0.55) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| SCHEMBL8675517 | 0.88 | KMT2A (0.61) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| SCHEMBL8464721 | 0.86 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8322433 | 0.86 | RAB9A (0.58) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8406785 | 0.84 | MEN1 (0.55) | LMNANPC1POLBRAB9AMAPK14 | |
| SCHEMBL8325122 | 0.82 | POLB (0.56) | PTGER1LMNANPC1POLBRAB9A | |
| SCHEMBL8321384 | 0.81 | PTGER1 (0.77) | PTGER1PTGER4PTGER3PTGER2ABCB1 | |
| SCHEMBL8321954 | 0.81 | PTGER1 (0.69) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8322098 | 0.81 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| SCHEMBL8327425 | 0.80 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |