⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL9341916 | 0.97 | CA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL10757589 | 0.97 | CA1 (0.36) | — | |
| SCHEMBL1165099 | 0.92 | CA1 (0.33) | — | |
| SCHEMBL31448055 | 0.85 | SOS1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL10900014 | 0.83 | MAPK10 (0.40) | — | |
| SCHEMBL1304591 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL11205797 | 0.79 | — | — | |
| SCHEMBL5370217 | 0.78 | — | — | |
| SCHEMBL5380526 | 0.78 | — | — | |
| SCHEMBL13567593 | 0.73 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1475471-A | 1-aryl-2 perluoro or polyfluoro phenyl ethylene and its derirative, its synthesis and application | 中国科学院上海有机化学研究所 | 2004-02-18 | — | — | CN | claimed |
| EP-0649831-B1 | Process for the preparation of 3-(p-fluorphenyle)-2-methylepropionic acid and of derivatives of 3-(p-fluorphenyle)-2-methylepropionic acid | HOECHST AG (DE) | 1998-10-14 | — | — | EP | claimed |
| US-5675034-A | Process for preparing 2-(p-fluorophenyl)-2 methyl-propionic acid and 3-(p-fluorophenyl)-2-methylpropionic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | claimed |
| WO-1991013847-A1 | PROCESS FOR PREPARING CHLORO-DIFLUOROBENZENE | ISC CHEMICALS LIMITED (GB) | 1991-09-19 | — | — | WO | claimed |
| EP-0447259-A1 | Process for preparing chloro-difluorobenzene | ISC CHEMICALS LIMITED (GB) | 1991-09-18 | — | — | EP | claimed |
| JP-2250845-A | — | — | None | — | — | JP | disclosed |
| JP-7233120-A | — | — | None | — | — | JP | disclosed |
| CN-119118896-A | Preparation method of sulphone gamma-butyrolactam | 中国科学院西北高原生物研究所 | 2024-12-13 | — | — | CN | disclosed |
| CN-118834121-A | Method for preparing biaryl compound by cross-coupling of diazonium salt and aryl bromide under nickel catalysis | 浙江工业大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-117263841-A | Preparation method of sulphone gamma-butyrolactam | 中国科学院西北高原生物研究所 | 2023-12-22 | — | — | CN | disclosed |
| CN-111039905-B | Preparation method of 5-methyl-5-phenyl-4-arylsulfonyl-furan-2 (5H) -one compound | 嘉兴学院 | 2022-11-18 | — | — | CN | disclosed |
| CN-113024430-A | Process for converting substituted arylamines to arylazomethylsulfones | 天津师范大学 | 2021-06-25 | — | — | CN | disclosed |
| US-5675034-A | Process for preparing 2-(p-fluorophenyl)-2 methyl-propionic acid and 3-(p-fluorophenyl)-2-methylpropionic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | disclosed |
| US-5675034-A | Process for preparing 2-(p-fluorophenyl)-2 methyl-propionic acid and 3-(p-fluorophenyl)-2-methylpropionic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | disclosed |
| EP-0596684-B1 | Preparation of substituted aryl compounds | GREAT LAKES FINE CHEM LTD (GB) | 1997-01-29 | — | — | EP | disclosed |
| JP-H07233120-A | PREPARATION OF 3-(P-FLUOROPHENYL)-2-METHYLPROPIONIC ACID AND 3-(P-FLUOROPHENYL)-2-METHYLPROPIONIC ACID DERIVATIVE | HOECHST AG | 1995-09-05 | — | — | JP | disclosed |
| US-5416235-A | Preparation of substituted aryl compounds | OCTEL CHEMICALS LIMITED (GB) | 1995-05-16 | — | — | US | disclosed |
| EP-0649831-A1 | Process for the preparation of 3-(p-fluorphenyle)-2-methylepropionic acid and of derivatives of 3-(p-fluorphenyle)-2-methylepropionic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-26 | — | — | EP | disclosed |
| EP-0596684-A1 | Preparation of substituted aryl compounds | GREAT LAKES FINE CHEMICALS LIMITED (GB) | 1994-05-11 | — | — | EP | disclosed |
| JP-H02250845-A | PRODUCTION OF 3-(4-FLUOROPHENYL)PROPIONALDEHYDE | SUMITOMO PHARMACEUT CO LTD | 1990-10-08 | — | — | JP | disclosed |