Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.51 |
| ▸ | DRD3 | P35462 | 7/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328043 | 0.80 | CYP19A1 (0.50) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20573750 | 0.75 | S1PR5 (0.53) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL9005649 | 0.74 | PTGIR (0.54) | PTGIR | |
| SCHEMBL8410725 | 0.74 | CHRM2 (0.61) | DRD2DRD3DRD4 | |
| SCHEMBL3316599 | 0.74 | DRD2 (0.62) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3316605 | 0.74 | DRD2 (0.62) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3320908 | 0.74 | DRD2 (0.62) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL2256731 | 0.73 | CYP11B1 (0.33) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17390264 | 0.73 | CYP11B1 (0.33) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL22071078 | 0.72 | DRD2 (0.46) | DRD2DRD3HTR1DDRD4HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |