Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325013 | 0.86 | EDNRB (0.43) | EDNRAEDNRB | |
| SCHEMBL27424258 | 0.86 | EDNRB (0.48) | EDNRAEDNRB | |
| SCHEMBL7327055 | 0.83 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7330749 | 0.83 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7333240 | 0.82 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7329858 | 0.82 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL7332438 | 0.81 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7328712 | 0.80 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7327165 | 0.80 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL7331793 | 0.79 | EDNRA (0.49) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |