Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214684 | 0.93 | TDP1 (0.49) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4581242 | 0.86 | TDP1 (0.59) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28449486 | 0.86 | TDP1 (0.59) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1233843 | 0.86 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1553324 | 0.84 | TDP1 (0.61) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8324987 | 0.82 | TDP1 (0.64) | TDP1L3MBTL1CYP1A2CYP2C19CHRM2 | |
| SCHEMBL8332453 | 0.82 | TDP1 (0.64) | TDP1L3MBTL1CYP1A2CYP2C19CHRM2 | |
| SCHEMBL1553659 | 0.82 | TDP1 (0.64) | TDP1L3MBTL1CYP1A2CYP2C19CHRM2 | |
| SCHEMBL3843934 | 0.82 | TDP1 (0.64) | TDP1L3MBTL1CYP1A2CYP2C19CHRM2 | |
| SCHEMBL8328633 | 0.82 | TDP1 (0.64) | TDP1L3MBTL1CYP1A2CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965477-A | Process for the preparation of supported metallocene catalyst | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1999-10-12 | — | — | US | disclosed |
| EP-0878486-A1 | A process for the preparation of supported metallocene catalyst | Council of Scientific and Industrial Research (IN) | 1998-11-18 | — | — | EP | disclosed |