Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GLS | O94925 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581242 | 1.00 | TDP1 (0.59) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16295516 | 0.92 | SMN1; SMN2 (0.51) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16295518 | 0.92 | SMN1; SMN2 (0.51) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28985362 | 0.92 | MGLL (0.55) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL8008707 | 0.90 | MGLL (0.62) | TDP1L3MBTL1 | |
| SCHEMBL8008712 | 0.90 | MGLL (0.62) | TDP1L3MBTL1 | |
| SCHEMBL18396493 | 0.90 | TDP1 (0.53) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17732266 | 0.90 | TDP1 (0.53) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18396492 | 0.90 | TDP1 (0.53) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17732265 | 0.90 | TDP1 (0.53) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109794292-B | Z-selective ruthenium carbene olefin metathesis catalyst, and preparation method and application thereof | 天津大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-108659049-B | Z-selective ruthenium olefin metathesis catalyst, preparation method and application | 天津大学 | 2020-09-01 | — | — | CN | disclosed |