Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.82 |
| ▸ | ITGAV | P06756 | 20/20 | 0.82 |
| ▸ | ITGB6 | P18564 | 15/20 | 0.82 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.71 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.71 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.71 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.71 |
| ▸ | ITGA8 | P53708 | 3/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336297 | 0.91 | ITGB3 (0.82) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL8325975 | 0.91 | ITGB3 (0.82) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6226399 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6226396 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL8336369 | 0.85 | ITGB3 (0.82) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL8326989 | 0.85 | ITGB3 (0.82) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL8327281 | 0.85 | ITGB3 (0.68) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6265972 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6270500 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6225812 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060376-A1 | THE R-ISOMER OF BETA AMINO ACID COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPRATION (US) | 2004-07-22 | — | — | WO | disclosed |