Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329771 | 1.00 | NR1H2 (0.33) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL8329335 | 0.81 | CHRM2 (0.37) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL8329981 | 0.81 | CHRM2 (0.37) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL8326060 | 0.81 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL8331008 | 0.81 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL8488452 | 0.78 | NR1H2 (0.49) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL9189316 | 0.78 | NR1H2 (0.49) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL8486841 | 0.78 | NR1H2 (0.49) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL14764516 | 0.74 | CHRM2 (0.41) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL4435193 | 0.74 | CHRM2 (0.33) | NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551653-B1 | Enantiomeric pure cis-2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation | BAYER AG (DE) | 1999-03-17 | — | — | EP | disclosed |
| EP-0592868-A1 | Quinolonecarboxylic acids | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0591808-A1 | Quinolonecarboxylic acids | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0551653-A1 | Enantiomeric pure 2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |
| EP-0550903-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1993-07-14 | — | — | EP | disclosed |