Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189316 | 1.00 | NR1H2 (0.49) | NR1H2PIK3CDCHRM2CHRM1CHRM3 | |
| SCHEMBL8486841 | 1.00 | NR1H2 (0.49) | NR1H2PIK3CDCHRM2CHRM1CHRM3 | |
| SCHEMBL15729247 | 0.86 | NR1H2 (0.43) | NR1H2PIK3CDCHRM2CHRM1CHRM3 | |
| SCHEMBL21216453 | 0.85 | NR1H2 (0.48) | NR1H2PIK3CDCHRM2CHRM1CHRM3 | |
| SCHEMBL8184654 | 0.85 | NR1H2 (0.48) | NR1H2PIK3CDCHRM2CHRM1CHRM3 | |
| SCHEMBL23555640 | 0.84 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL20031521 | 0.84 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL14969670 | 0.84 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL18309942 | 0.82 | NR1H2 (0.46) | NR1H2PIK3CDCHRM2CHRM1CHRM3 | |
| SCHEMBL2384096 | 0.81 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2NAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004956-A | CHEMICAL INTERMEDIATES FOR BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| US-5532364-A | FROM A DIHYDROPYRIDINE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| US-5480879-A | ANTIBACTERIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5436334-A | Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-25 | — | — | US | disclosed |