⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832612 | 0.91 | — | — | |
| SCHEMBL832257 | 0.80 | — | — | |
| SCHEMBL2345603 | 0.73 | FDPS (0.40) | — | |
| SCHEMBL2170444 | 0.73 | — | — | |
| SCHEMBL9020667 | 0.73 | — | — | |
| SCHEMBL5528900 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL5523111 | 0.73 | TSHR (0.40) | — | |
| Phosphonic Acid SCHEMBL27492827 | 0.73 | FDPS (0.41) | — | |
| SCHEMBL9788426 | 0.73 | FDPS (0.37) | — | |
| SCHEMBL226926 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908466-B1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2014-02-19 | — | — | EP | disclosed |
| US-8497397-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-30 | — | — | US | disclosed |
| EP-1880720-B1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-8344029-B2 | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120220593-A1 | Substituted Acrylamide Derivative and Pharmaceutical Composition Comprising the Same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
| US-8143446-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20090292024-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090118199-A1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAIICHI SANKYO COMPANY , LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1908466-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-04-09 | — | — | EP | disclosed |
| EP-1880720-A1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| US-5847034-A | Porphyrin-containing silicones having increased thermal stability | WACKER-CHEMIE GMBH (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5055502-A | Storage stable, moisture curable to elastomers | RHONE-POULENC CHIMIE (FR) | 1991-10-08 | — | — | US | disclosed |
| EP-0235049-B1 | TIN-BASED CATALYST MIXTURE FOR ROOM TEMPERATURE VULCANISABLE POLYSILOXANE COMPOSITIONS | RHONE-POULENC CHIMIE (FR) | 1990-07-11 | — | — | EP | disclosed |
| EP-0354138-A1 | Process for preparing diorganopolysiloxanes containing terminal alkoxy groups | RHONE-POULENC CHIMIE (FR) | 1990-02-07 | — | — | EP | disclosed |
| US-4849388-A | DIORGANOTIN BIS/2-DIKETONATE/ | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-07-18 | — | — | US | disclosed |
| US-4749766-A | Organotin curing catalyst for vulcanizable organopolysiloxanes | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-06-07 | — | — | US | disclosed |
| EP-0235049-A1 | Tin-based catalyst mixture for room temperature vulcanisable polysiloxane compositions | RHONE-POULENC CHIMIE (FR) | 1987-09-02 | — | — | EP | disclosed |