Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330243 | 0.99 | ACAT1 (0.54) | ACAT1SOAT1PDE4AKCNH2GPR132 | |
| SCHEMBL8329858 | 0.96 | ACAT1 (0.56) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8326834 | 0.93 | ACAT1 (0.53) | ACAT1SOAT1GPR132 | |
| SCHEMBL8329443 | 0.90 | ACAT1 (0.56) | ACAT1SOAT1 | |
| SCHEMBL8325092 | 0.89 | ACAT1 (0.61) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8324086 | 0.88 | ACAT1 (0.58) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8321469 | 0.87 | ACAT1 (0.65) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8329116 | 0.87 | ACAT1 (0.60) | ACAT1SOAT1 | |
| SCHEMBL8323036 | 0.87 | ACAT1 (0.57) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8327845 | 0.87 | ACAT1 (0.57) | ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |