Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.50 |
| ▸ | PGR | P06401 | 7/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.50 |
| ▸ | AR | P10275 | 7/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091123 | 0.90 | PARP14 (0.45) | NR3C1PGRNR3C2ARPARP14 | |
| SCHEMBL6090427 | 0.82 | NR3C1 (0.67) | NR3C1PGRNR3C2AR | |
| SCHEMBL6091497 | 0.80 | NR3C1 (0.47) | NR3C1PGRNR3C2AR | |
| SCHEMBL6088952 | 0.79 | NR3C1 (0.52) | NR3C1PGRNR3C2AR | |
| SCHEMBL6089364 | 0.79 | NR3C1 (0.39) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL6089244 | 0.77 | NR3C1 (0.39) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL6091511 | 0.77 | NR3C1 (0.40) | NR3C1PGRNR3C2ARKDM4E | |
| SCHEMBL6091351 | 0.76 | NR3C1 (0.48) | NR3C1PGRNR3C2AR | |
| SCHEMBL6091991 | 0.75 | AR (0.38) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL6090466 | 0.75 | DNA2 (0.42) | NR3C1PGRNR3C2ARPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |