Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367374 | 0.82 | HPGD (0.48) | HPGDNSD2AKR1C3SMN1; SMN2LMNA | |
| SCHEMBL7370504 | 0.73 | MAPK8 (0.50) | HPGDSMN1; SMN2LMNAGAA | |
| SCHEMBL7847928 | 0.71 | HPGD (0.55) | HPGDHDAC6CYP1A2CYP2C19KMT2A | |
| SCHEMBL7370502 | 0.67 | MAPK8 (0.62) | HPGDCYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL12844507 | 0.66 | NSD2 (0.63) | HPGDNSD2KMT2ALMNAGAA | |
| SCHEMBL8376695 | 0.66 | HPGD (0.61) | HPGDNSD2HDAC6CYP1A2CYP3A4 | |
| SCHEMBL7366732 | 0.66 | HPGD (0.61) | HPGDKMT2APOLBSMN1; SMN2LMNA | |
| SCHEMBL7373017 | 0.66 | MAPK8 (0.60) | HPGDKMT2APOLBSMN1; SMN2LMNA | |
| SCHEMBL7399781 | 0.66 | MAPK8 (0.57) | HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL7365200 | 0.65 | MAPK8 (0.62) | HPGDSMN1; SMN2LMNAMAPTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047817-A1 | PDE4 AND PDE3/4 INHIBITORS FOR USE IN THE TREATMENT OF CACHEXIA | ALTANA PHARMA AG (DE) | 2004-06-10 | — | — | WO | disclosed |