Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555949 | 0.80 | TBXAS1 (0.55) | TBXAS1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10617438 | 0.70 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10617444 | 0.70 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10632145 | 0.70 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL9825437 | 0.70 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL9825243 | 0.70 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL9825241 | 0.70 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10635075 | 0.70 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL10635070 | 0.70 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL8807682 | 0.69 | TBXAS1 (0.60) | TBXAS1LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |