Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | ME2 | P23368 | 1/20 | 0.62 |
| ▸ | ME1 | P48163 | 1/20 | 0.62 |
| ▸ | ME3 | Q16798 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068444 | 0.90 | FKBP1A (0.82) | FKBP1ANPC1TDP1POLBSMN1; SMN2 | |
| SCHEMBL1953978 | 0.89 | FKBP1A (0.80) | FKBP1ANPC1TDP1POLBSMN1; SMN2 | |
| SCHEMBL9556702 | 0.88 | FKBP1A (0.78) | FKBP1ANPC1TDP1POLBSMN1; SMN2 | |
| SCHEMBL7131839 | 0.88 | NPC1 (0.86) | FKBP1ANPC1TDP1POLBME2 | |
| SCHEMBL25432319 | 0.84 | NPC1 (0.93) | FKBP1ANPC1TDP1POLBME2 | |
| SCHEMBL3700679 | 0.84 | NPC1 (1.00) | FKBP1ANPC1TDP1POLBME2 | |
| SCHEMBL9557082 | 0.84 | FKBP1A (0.72) | FKBP1AME2ME1ME3SMN1; SMN2 | |
| SCHEMBL10195739 | 0.84 | FKBP1A (0.72) | FKBP1ASMN1; SMN2RAB9AKMT2ATSHR | |
| SCHEMBL8391980 | 0.84 | FKBP1A (0.72) | FKBP1ANPC1TDP1KMT2ANAAA | |
| SCHEMBL15455557 | 0.84 | FKBP1A (0.72) | FKBP1ANPC1TDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111960962-B | Nickel-catalyzed alpha-alkylation method of acetamide and thioacetamide | 山东师范大学 | 2023-03-07 | — | — | CN | disclosed |
| EP-3313397-B1 | PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | MERCK SHARP & DOHME (US) | 2020-11-25 | — | — | EP | disclosed |
| CN-111960962-A | Nickel-catalyzed alpha-alkylation method of acetamide and thioacetamide | 山东师范大学 | 2020-11-20 | — | — | CN | disclosed |
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |