Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL22497667 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL7058918 | 1.00 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL3068491 | 1.00 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL4280141 | 1.00 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL1318750 | 1.00 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL131261 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL28841734 | 0.96 | TDP1 (0.77) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL28316305 | 0.96 | TDP1 (0.77) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL28486346 | 0.96 | TDP1 (0.77) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL28309882 | 0.96 | TDP1 (0.77) | TDP1TSHRALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294831-B | Preparation method of elastic thermochromic material for intelligent window, product and application thereof | 南京大学 | 2021-08-13 | — | — | CN | claimed |
| CN-115884999-A | Functionalized thermoplastic polyurethanes, methods of producing the same, methods of producing highly functionalized medical composites using the same, and medical devices comprising the same | 爱-森新株式会社 | 2023-03-31 | — | — | CN | disclosed |
| CN-109415533-B | Rubber composition, its manufacture and use | 巴斯夫欧洲公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-110294831-B | Preparation method of elastic thermochromic material for intelligent window, product and application thereof | 南京大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-113021732-A | Intelligent air bag and manufacturing method thereof | 陕西天翌天线股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-10077413-B2 | Lubricating composition containing a detergent | THE LUBRIZOL CORPORATION (US) | 2018-09-18 | — | — | US | disclosed |
| US-20160208189-A1 | LUBRICATING COMPOSITION CONTAINING A DETERGENT | THE LUBRIZOL CORPORATION | 2016-07-21 | — | — | US | disclosed |
| US-20160060562-A1 | 2-STROKE INTERNAL COMBUSTION ENGINE CYLINDER LINER LUBRICATING COMPOSITION | LUBRIZOL CORP (US) | 2016-03-03 | — | — | US | disclosed |
| US-6003987-A | Ink set recording apparatus and method using ink set having a dye that becomes insoluble when mixed with another dye | CANON KABUSHIKI KAISHA (JP) | 1999-12-21 | — | — | US | disclosed |
| US-5833963-A | Non-tacky and quick-drying aqueous-based antiperspirant compositions | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-4518522-A | DI-(ALKYL OR ALKOXYALKYL) MALONATES AND CONTAINING A STABILIZING MONOFUNCTIONAL REACTIVE COMPOUND | MOBAY CHEMICAL CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |