Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL6562957 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Octanedioate SCHEMBL9183306 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Azelaic Acid SCHEMBL9181939 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL3137967 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL4369554 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL9820842 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL5146021 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL11050745 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL1194225 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL3685228 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958815-A | HYDROLYTIC CONDENSATION OF: CHELATING POLAR SOLVENT, LEAD CARBOXYLATES, TITANIUM AND/OR ZIRCONIUM TETRAALKOXIDES; AGING BEYOND GEL POINT, REPLACING SOLVENT WITH LOW POLARITY NONCHELATING SOLVENT, SUPERCRITICAL DRYING, TEMPERING AEROGEL | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5656073-A | Molded article based on PZT (Pb(Zr,Ti)03, lead zirconate-lead titanate), method and intermediate product for its manufacture | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5578539-A | Molded article based on PZT (Pb(Zr,Ti)O3, lead zirconate-lead titanate), method and intermediate product for its manufacture | Fraunhofer-Gesellschaft zur F orderung der angewandten Forschung e.V. (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5463086-A | Dissolving a crude lactide in a weak and strong solvent mixture then recrystallizing | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1995-10-31 | — | — | US | disclosed |
| US-5354514-A | Heating mixture of thioamide compound and copper- or lead-containing compound | JUJO PAPER CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| US-5270366-A | Lead stabilized, flexible polymeric blends containing polyvinylchloride | VISTA CHEMICAL COMPANY (US) | 1993-12-14 | — | — | US | disclosed |
| US-4207218-A | ANTICAKING AGENTS, STORAGE STABILITY | THE B. F. GOODRICH COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-3953480-A | Epoxidation of olefins by hydrogen peroxide | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-04-27 | — | — | US | disclosed |