SCHEMBL832810

SCHEMBL832810

CC(C)c1cc(N)c(C(C)C)cc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
POLB P06746 1/20 0.46
GFER P55789 1/20 0.46
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
HIF1A Q16665 2/20 0.37
ALDH1A1 P00352 1/20 0.37
ALOX12 P18054 1/20 0.37
HTT P42858 1/20 0.37
GABRA1 P14867 6/20 0.36
GABRB1 P18505 4/20 0.36
GABRB2 P47870 4/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
PTK2 Q05397 1/20 0.35
LMNA P02545 2/20 0.33
SLC6A2 P23975 2/20 0.33
HTR2B P41595 2/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117750 0.90 PTK2 (0.41) GAAPOLBGFERCA1CA2
SCHEMBL18135464 0.87 GAA (0.46) GAAPOLBGFERCA1CA2
SCHEMBL3649606 0.87 POLB (0.59) GAAPOLBGFERHIF1AALDH1A1
SCHEMBL24869453 0.84 LMNA (0.42) GAAPOLBGFERCA1CA2
SCHEMBL11792033 0.84 POLB (0.42) GAAPOLBGFERCA1CA2
SCHEMBL26137554 0.84 GAA (0.38) GAAPOLBGFERCA1CA2
SCHEMBL12289335 0.83 CYP3A4 (0.50) GAAPOLBGFERCA1CA2
SCHEMBL5379465 0.83 POLB (0.37) GAAPOLBGFERCA1CA2
SCHEMBL15165728 0.81 GAA (0.35) GAAPOLBGFERCA1CA2
SCHEMBL20017590 0.81 GAA (0.44) GAAPOLBGFERCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
CN-111433683-B Toner for developing electrostatic image and method for producing the same 日本瑞翁株式会社 2023-11-24 CN disclosed
CN-111240165-B Toner binder and toner 三洋化成工业株式会社 2023-06-27 CN disclosed
EP-3623870-B1 IMAGE FORMING APPARATUS AND TONER SET RICOH CO LTD (JP) 2022-05-04 EP disclosed
US-11281117-B2 Toner for electrostatic-image development and method for manufacturing same ZEON CORPORATION (JP) 2022-03-22 US disclosed
EP-3418811-B1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD FOR MANUFACTURING TONER RICOH CO LTD (JP) 2021-07-28 EP disclosed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-10895816-B2 Image forming apparatus and toner set RICOH COMPANY, LTD. (JP) 2021-01-19 US disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
US-20200348609-A1 TONER FOR ELECTROSTATIC-IMAGE DEVELOPMENT AND METHOD FOR MANUFACTURING SAME ZEON CORPORATION (JP) 2020-11-05 US disclosed
US-4820743-A BLEND OF POLYETHERPOLYOL AND POLYAMINE, AND UNSATURATED MONOMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-11 US disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0075130-B1 IMPROVED REACTION INJECTION MOLDING PROCESS THE DOW CHEMICAL COMPANY (US) 1986-09-17 EP disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed