Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPR3 | P17342 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12234276 | 0.81 | CTSK (0.38) | CTSKTDP1POLBNPSR1CA1 | |
| SCHEMBL25453631 | 0.81 | CTSK (0.41) | CTSKTDP1POLBNPSR1CA1 | |
| SCHEMBL22316563 | 0.81 | CTSK (0.38) | CTSKMEN1KMT2AGAACYP1A2 | |
| SCHEMBL19764839 | 0.80 | CTSK (0.39) | CTSKTDP1POLBNPSR1CA1 | |
| SCHEMBL16387553 | 0.79 | CTSK (0.46) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL13422140 | 0.79 | CTSK (0.46) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL27133818 | 0.79 | CTSK (0.46) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL12234278 | 0.79 | CTSK (0.43) | CTSKTDP1POLBNPSR1NOS1 | |
| SCHEMBL13011701 | 0.78 | CTSK (0.42) | CTSKTDP1POLBNPSR1MEN1 | |
| SCHEMBL25453619 | 0.77 | CYP2D6 (0.44) | CTSKTDP1POLBNPSR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |