SCHEMBL832826

SCHEMBL832826

[CH2]C(CCCCCCC)OC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.41
DNM1 Q05193 2/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
CA2 P00918 1/20 0.39
OPRM1 P35372 1/20 0.39
SMPD1 P17405 3/20 0.38
LSS P48449 1/20 0.37
FDPS P14324 3/20 0.37
GPR84 Q9NQS5 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10526727 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL11641249 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL17509529 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL7431156 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL22207425 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL10555139 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL9716390 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL7440456 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL22207114 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB
SCHEMBL28920649 1.00 LMNA (0.41) LMNAZDHHC7DNM1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937650-B1 HETEROCYCLIC COMPOUNDS S BIO PTE LTD (SG) 2011-06-15 EP claimed
US-20100098691-A1 COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT S'BIO PTE LTD (SG) 2010-04-22 US claimed
EP-2131840-A1 COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT S*Bio Pte Ltd (SG) 2009-12-16 EP claimed
US-20090048300-A1 Heterocyclic Compounds S*BIO PTE LTD. (SG) 2009-02-19 US claimed
WO-2008108741-A1 COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT S*BIO PTE LTD (SG) 2008-09-12 WO claimed
EP-1937650-A1 HETEROCYCLIC COMPOUNDS S*Bio Pte Ltd (SG) 2008-07-02 EP claimed
WO-2007030080-A1 HETEROCYCLIC COMPOUNDS S*BIO PTE LTD (SG) 2007-03-15 WO claimed
EP-4382546-A1 POLY(UREA-URETHANE) POLYMER BASF SE (DE) 2024-06-12 EP disclosed
WO-2024105027-A1 CLOSED LOOP RECYCLING CONCEPT FOR COMPOSITES COMPRISING COVALENT ADAPTABLE POLY(UREA-URETHANE) NETWORKS WITH DYNAMIC HINDERED UREA BONDS BASF SE (DE) 2024-05-23 WO disclosed
CN-117964834-A Polyacrylate polymers 巴斯夫欧洲公司 2024-05-03 CN disclosed
WO-2024061814-A1 CONDITIONER WITH IMPROVED MANAGEABILITY WELLA GERMANY GMBH (DE) 2024-03-28 WO disclosed
EP-4342444-A1 CONDITIONER WITH IMPROVED MANAGEABILITY Wella Germany GmbH (DE) 2024-03-27 EP disclosed
EP-4334373-A1 TRIAZINE BASED ULTRAVOLET ABSORPTION POLYMER BASF SE (DE) 2024-03-13 EP disclosed
EP-2131840-A1 COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT S*Bio Pte Ltd (SG) 2009-12-16 EP disclosed
US-20090048300-A1 Heterocyclic Compounds S*BIO PTE LTD. (SG) 2009-02-19 US disclosed
WO-2008108741-A1 COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT S*BIO PTE LTD (SG) 2008-09-12 WO disclosed
EP-1937650-A1 HETEROCYCLIC COMPOUNDS S*Bio Pte Ltd (SG) 2008-07-02 EP disclosed
WO-2007030080-A1 HETEROCYCLIC COMPOUNDS S*BIO PTE LTD (SG) 2007-03-15 WO disclosed
EP-0314735-A1 LIQUID CRYSTAL MATERIAL THE GENERAL ELECTRIC COMPANY, p.l.c. (GB) 1989-05-10 EP disclosed
WO-1988008870-A1 LIQUID CRYSTAL MATERIAL THE GENERAL ELECTRIC COMPANY, P.L.C. (GB) 1988-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048300-A1 Heterocyclic Compounds HDAC1, HDAC3, HDAC11 LMNA 875/4885ZDHHC7 958/4885DNM1 2396/4885
US-20100098691-A1 COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT PAICS, HDAC5, HDAC4 LMNA 3157/4885ZDHHC7 1055/4885DNM1 3264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.