Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 6/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328308 | 1.00 | CHRM2 (0.57) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8324761 | 0.93 | KCNH2 (0.62) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8324766 | 0.93 | KCNH2 (0.62) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8321460 | 0.93 | ALDH1A1 (0.58) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8321462 | 0.93 | ALDH1A1 (0.58) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8318633 | 0.89 | KDM4E (0.52) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8318631 | 0.89 | KDM4E (0.52) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8326675 | 0.87 | CACNA1F (0.55) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8326670 | 0.87 | CACNA1F (0.55) | CHRM2DRD1DPP4KDM4ELMNA | |
| SCHEMBL8324721 | 0.86 | CHRM2 (0.60) | CHRM2DRD1DPP4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688772-B1 | Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG CHEMICAL LTD (KR) | 1999-05-06 | — | — | EP | disclosed |
| US-5869670-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1999-02-09 | — | — | US | disclosed |
| US-5840916-A | INTERMEDIATE FOR QUINOLONE ANTIBIOTICS; 4-AMINOMETHYL-3-METHOXYIMINOPYRROLIDINE | LG CHEMICAL LTD. (KR) | 1998-11-24 | — | — | US | disclosed |
| US-5698570-A | QUINOLONE ANTIBIOTIC; BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-12-16 | — | — | US | disclosed |
| US-5633262-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-05-27 | — | — | US | disclosed |
| EP-0688772-A1 | Novel quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG Chemical Limited (KR) | 1995-12-27 | — | — | EP | disclosed |