Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012169 | 0.82 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL2269491 | 0.81 | ADORA1 (0.50) | PKMPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5062073 | 0.80 | PDE4A (0.42) | PKMPDE4APDE4BPDE4CPDE4D | |
| Ammonia Solution, Strong SCHEMBL3664643 | 0.75 | KDM4E (0.39) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL30096766 | 0.75 | CSNK2A2 (0.49) | PKMPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2849211 | 0.74 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL2841387 | 0.73 | L3MBTL4 (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2543790 | 0.73 | L3MBTL4 (0.38) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL2840584 | 0.72 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DHTR7 | |
| SCHEMBL2272231 | 0.72 | PDE4A (0.49) | PKMPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| CN-1209744-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | CN | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |